can stress raise cea levelsrok aoe commanders
1998-2023 Mayo Foundation for Medical Education and Research. Everyone thinks, this was the cause of my CEA spike. Case in point, I mention my oncologist said in his practice 1 in 4 of his patients have exhibited high CEA levels (as high as 20) and not have any cancer as a result. As far as questions to ask your dr, I might ask if the test should be done again. CEA is a type of tumor marker used to monitor cancer. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Second, I'm just getting over having a bacterial infection as a side effect of the 2nd surgery. J Natl Compr Canc Netw. Diverticulitis . A high level of CEA can be a sign Diabetes, smoking, chronic obstructive pulmonary disease, and colonic polyps were considered as causes of false elevation. I am scared that a "wait and see" approach and re-test might show a skyrocketing increase in the number and that I should have done something when the number was only "slightly elevated". But if you already have a cancer diagnosis, your provider may use the test to guide or monitor your treatment. I received my first chemo therapy treatment on Oct 25th 2016 of 5-FU and oxyplatin with pump to take home with 46 hrs of 5-FU in it. A high level of CEA can be a sign of certain types of cancers. Would you mind me asking what stage your colon cancer was? Few people are aware that exercise, especially intense activity, can significantly alter certain laboratory tests. But as I said, we'll see if my oncologist is correct that he thinks the recent spike is probably nothing. Can stress raise CEA levels? It can also be increased during pregnancy. Retest done to make sure no lab error. Carcinoembryonic antigen (CEA), the level of which is known to increase in both patients with gastrointestinal cancers and those with non-neoplastic conditions, is one of the most widely-used tumor markers. That comes back clear. doi: 10.1097/01.cad.0000398728.45590.11. Heres some info from the American Association for Clinical Chemistry. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. @colleenyoung @diannechildress My CEA has been staying between 1.7 and 2.4 since my colon cancer was removed b on 1/16. Exercise is known to contribute to increased levels of potassium, urea, creatinine, creatine kinase, lactate dehydrogenase (LDH), aspartate aminotransferase (AST), alkaline phosphatase, bilirubin, uric acid, as well as the white blood cell count. Elevated serum CEA is not highly specific for colon cancer recurrence, while various other gastrointestinal disorders such as pancreatitis, peptic ulcer disease, biliary tract abnormalities (benign or malignant) and liver disorders may contribute to increased serum CEA and false-positive results . There's lots of scientific research to prove it. This past April I was in to my oncologist for my check-up and my level has increased to 6.1. Can stress raise CEA levels? I've had the same issue with Bayer vs Roche CEA measurements - I wish I had a good charcterization of the differences. We present the case of a patient, a 58-year-old male, who had initially presented aged 56 years with rectal bleeding for several months. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. CEA levels normally become very low or disappear after birth. A high level of CRP in the blood is a marker of inflammation. A retest was ordered to make sure that number was real.came back at 11. What happens to atoms during chemical reaction? Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. The false-positive rates of CEA according to level were as follows: 5.110.0 ng/mL, 99.5%; 10.115.0 ng/mL, 87.2%; 15.120.0 ng/mL, 100.0%; >20.0 ng/mL, 33.3%. I wish all the best and pray for all. Overtime, that would cause stress on blood vessels. Your CEA levels are all low. CEA is a type of tumor marker. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease. If the other tumor markers are down (which they are), then he is not concerned. The cancer had not gotten out of the colon area. Conditions that can cause an increase in CA 125 include many that aren't cancerous, such as menstruation and uterine fibroids. A false increase in CEA levels is seen immediately post radio/chemotherapy due to the death of tumor cells and CEA release. Can stress raise CEA levels? What questions or next steps would be reasonable to ask her? Interested in more discussions like this? For the study, a CEA flare was defined as a 15% rise from baseline (at least 4 ug/L), followed by a subsequent 15% decrease from baseline in CEA level within four to six weeks of initial treatment. I am going to see my GP in an hour. CEA has been a constant bane to me since my initial diagnosis in 2012. I stopped having it checked in 2013 as it was not a good indicator for me. He said in his practice he said about 1 in 4 of his patients being tracked with CEA will have high false positives. In some patients, the serum CEA level becomes positive in the absence of recurrence. There is very little risk to having a CEA blood test. Go to the Colorectal Cancer Support Group. I have mets to only my bones and I have been on Femara and Xgeva for almost 2 years. If your CEA levels significantly decrease throughout treatment, it often means your treatment is working. Six patients had at least three CEA values and four were included in the study. I am new to these discussion boards, and was diagnosed with stage 1 colon cancer in September 2016. Advertising on our site helps support our mission. Certain cancers may also cause an increased level of CA 125, including . This test isnt an accurate way to screen for it because many other diseases can cause the levels of this protein to rise. As with all tumor markers, trend over time is the more important factor than any single test. It statistically suggest a much higher probability of recurrence. This theory is not new, but it's certainly been proven to the point of absurdity. Thus, we suggest that exercise for 2-3 days per week decreases the expression of CEA and improves body condition, without loading fatigue or stress, which may contribute to preventing cancer in the elderly women. I continue to visit my dermatologist every 4-6 months, no additional melanoma has been found.in 11 years. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://medlineplus.gov/lab-tests/cea-test/), (https://www.nhs.uk/conditions/cea-test/), (https://www.nhlbi.nih.gov/health-topics/thoracentesis), Visitation, mask requirements and COVID-19 information, Pathology & Laboratory Medicine Institute (R. Tomsich). Accessed 4/11/2022. Keep us posted. CEA is a blood glycoprotein. What are normal CEA levels. So given my age and other causes I'm looking at an almost 30% chance of not being here in 5-7 yrs. undefined will no longer be visible to you including posts, replies, and photos. Can CEA levels fluctuate during chemotherapy? But one thing is for sure and I've seen a paper state this. 10 Do you need to empty your bladder before a CEA test? The carcinoembryonic antigen (CEA) test measures the level of CEA in the blood. Use an X-ray image to guide the needle to the correct position. The cookie is used to store the user consent for the cookies in the category "Other. Request Consultation; . Mine hadnt gone over 3 until I had the remaining colon removed. High CEA levels dont necessarily mean you have cancer. Also, recent study results suggested that serum CEA levels may be related to insulin resistance or low-grade inflammation. In addition, levels >20 ng/ml before therapy may be associated with cancer which has already spread (metastatic disease). ), Betsy (who was diagnosed Stage 4 in 2005 and is still here and off chemo), I finally got down to a 1.8 after the last surgery, then it went to 2, then 2.2, then 2.6, it just kept bumping up. You also have the option to opt-out of these cookies. And we here on the forum are happy to let you know that you can chill. If you want to talk about CEA panic, imagine having to deal with not a few tenths rise but several points of rise. Your increase is very small too, so I would suspect stress might be the issue there. When You Breathe In Your Diaphragm Does What. All should be well. Policy. My follow up is every three months bloodwork and every six months CT scans. Do you see the paradox in all of this? And the cancerous polyp I had was in situ with only the surface of the polyp having cancerous cells. can stress raise cea levels. Of clinical importance is the influence of liver disease on the interpretation of CEA. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. Elevated serum CEA is not highly specific for colon cancer recurrence, while various other gastrointestinal disorders such as pancreatitis, peptic ulcer disease, biliary tract abnormalities (benign or malignant) and liver disorders may contribute to increased serum CEA and false-positive results [2]. Lots of things can make it go up further than that - and still not be tumor growth. I can certainly understand your concern about the increase", "@spedteacher At the request of @hopeful33250 I am responding to you. CEA levels decreased, were maintained, or increased by <20% versus baseline in 33 patients, and increased by >20% in 15. Here I am with just about the same amount of activity as when I was first diagnosed. a signal of prostate disease, was three times higher for men with high levels of stress! This cookie is set by GDPR Cookie Consent plugin. In many documents, they state well differentiated tumor cells express a lot of CEA. Doctors dont use the CEA test to make a first-time diagnosis of cancer. But I've NEVER had a CEA below 1.0. Just bumped to 4. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. Healthy cells also may make tumor markers in very low levels. Over the next 7 years I was having regular colonoscopies and the doctor removed polyps every time. Conditions such as smoking infection pregnancy and various inflammatory diseases can all cause an increase in CEA levels.The normal range for CEA levels is 0-5 ng/mL. Hi Diane 3. I had 2 follow ups since the surgery. The anxiety and concern you have should also be conveyed, especially if you have been a patient of this dr for a while. If you have values that are that high, it doesnt mean you have cancer. Cochrane reviews (highly respected meta-studies that are often used as guidelines) suggest a CEA of 10 as a trigger to start looking for recurrence. CR.I'm so sorry about your Mom even if you didn't have cancer that would have been so stressful to go through but you have mets to cope with on top of losing one of the most important people in your life. What can cause a false positive CEA? Sometimes a test result that is above 40 is considered proof that breast cancer has spread, but this isn't always the case. government site. Depending on the lab, the new normal CEA level is anywhere from 4 to 5. Does that fit in you case? I've been off of chemo since December 15, 2016 and my CEA has gradually moved from 1.2 in December to 3.4 yesterday. Although much research has been done to understand the molecular structure of CA 125, its function remains a source of much speculation. Fast forward to my recent check up just over a month ago. In remission, you may need regular CEA tests to watch for possible recurrences. I wish you the best sorry I couldnt help with any additional information. Yes, CEA can increase due to many non-cancer factors including just being stressed/run-down. Does anyone have a similar experience to this? This test isn't an accurate way to screen for it because many other diseases can cause the levels of this protein to rise . Would you like email updates of new search results? By clicking Accept All, you consent to the use of ALL the cookies. Of course, it may take some time to put all the pieces of the puzzle together. Your healthcare provider may use a CEA test to: A CEA test is usually a blood test. All my other blood work has come in between 5 to 6. Less commonly, your provider may test fluid from your: In these cases, your provider takes a small fluid sample using a needle or syringe. My perioperative CEA was 5.8 (August 2016, non-smoker). Colonoscopy. What are the physical state of oxygen at room temperature? As a result, this test cannot establish a cancer diagnosis on its own and is not used as a general screening tool for cancer. If CEA levels are high initially but then decrease, it may show that the treatment is having an effect. Your provider will combine it with physical examination and imaging as needed. Hello Ginger, Reasons for exclusion were the absence of CEA levels in the post-COVID-19 period (n = 1), the observed transient increase did not rise above normal range (n = 1), and radiographic evidence of cancer progression (n = 1). Therefore, false-positive results can result in unnecessary radiation exposure, costs, and anxiety. While the kink in the intestine and the allergic reaction dont sound like fun, Im also glad that these things were discovered now too. I hope you get them sorted soon. HHS Vulnerability Disclosure, Help Thanks for telling us about the results of the CT scan. Tumor markers are substances that are either made by cancer or made by the body in response to cancer. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. This has been going on for the past 2 years. Their levels can be elevated even in well controlled disease. I've been dealing with higher than normal CEA for now coming up on 4.5 years. These include cancers of the colon and rectum, prostate, ovary, lung, thyroid, or liver. Thank you and I will let you know when I have some news to share. So far none of my doctors have suggested using those other blood tests. I am ER+, PR+ and HER2 Neg. A carcinoembryonic antigen (CEA) test measures CEA, a specific blood protein. Talked to my CRC surgeon about what is going on. I'm tagging a few other members who may also have experience", "@colleenyoung @diannechildress My CEA has been staying between 1.7 and 2.4 since my colon cancer was". Yeah - there are several studies that show a pretty high false-positive rate for CEA in ppl like us who have had a resection. The only thing they found was a kink in my intestine which could cause some problems with constipation and stomach pain. My oncologist orders my blood work to be done every 3 weeks and always includes the CEA test as well Back in 2009, I had stage 3 melanoma with a 2% penetration into one lymph node. When you get there.don't pay too much on that TM test. Although an elevated level of a tumor marker may suggest the presence of cancer, this alone is not enough to . It is not a substitute for professional medical advice. CA 19-9 levels decreased, were maintained, or increased by <20% in 39 patients, and increased by >20% in 9. 2022 Aug 25;9:945433. doi: 10.3389/fmed.2022.945433. Carcinoembryonic antigen blood . Drinking a lot of caffeine from coffee or green tea can also affect some blood test results. At this point I have a 10% chance of being here in three years based on stats. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Thank you for all the repsonses regarding CEA blood test. Do you need to empty your bladder before a CEA test? We all get caught up in the stats, it is difficult not to when you are dealing with this. I asked him how common is it. The .gov means its official. I was due for my 3 year colonoscopy. Others include cancers of the pancreas, stomach, breast, lung, and medullary carcinoma of the thyroid and ovarian cancer.Benign conditions which can elevate CEA include smoking, infections, inflammatory bowel disease . We also use third-party cookies that help us analyze and understand how you use this website. My cancer was stage 1, T2 with 27 clean lymph nodes and low grade tumor. Evaluate how well cancer treatment is working. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. They are available on this number 0808 800 4040, Monday - Friday, between 9 a.m - 5 p.m. I believe this is called cell apoptosis (sp?). I just starting to comprehend all this and dont understand all of it but as long as blood levels are good and liver functions are normal. Attaches a vial or test tube to the needle. The most common elevated liver enzymes found in bloodstreams are: Alanine transaminase. Those are only odds, but they mean something. But this test isnt used in isolation. Your email address will not be published. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. If you have values that are that high, it doesnt mean you have cancer. Case Report: CEA Elevation Can Be a Marker of Increased Inflammation During Treatment with Oxaliplatin. Complete your request online or contact us by phone. "Chronic stress also can help cancer grow and spread in a number of ways," Sood says. "Hi Dianne, Welcome to Connect. It sounds like you are feeling good otherwise, but your concern is about the increase in the CEA numbers. Can stress raise CEA levels? This does help make me feel better. Pathology report was clean. Stress, Chronic Stress, and Stress Relief. CEA is an antigen (small protein) that is found on the surface of colon, rectal, gastric and other types of cancer cells and high levels of CEA can be detected in the blood of some patients with cancer and the developing fetus. Unable to load your collection due to an error, Unable to load your delegates due to an error. I am aware(via reading others' posts that in the scheme of things, my CEA number is not a huge "red flag or alarm" but it is to me. We redid the test again in 6 weeks which was yesterday and they have increased by 0.3 to 6.4. That would be a simple first step. Spinal cord (cerebrospinal fluid or CSF). A CEA test measures your levels of CEA. There are loads of studies looking for better markers, but sadly for us that's still a 'future'. So we're all scratching our heads wondering what is going on. The impact of carcinoembryonic antigen flare in patients with advanced colorectal cancer receiving first-line chemotherapy. Scientists first discovered CEA in 1968 when they isolated extracts of liver metastasized by colorectal cancer and also from normal fetal digestive tract. Ok. can cause it to rise. Truth is of course, that your CEA, like your weight, can fluctuate for no reason at all. Thanks for your help. Im tagging a few other members who may also have experience with fluctuating CEA levels. Oxaliplatin is a platinum-based chemotherapy that is an integral part of several regimens for colorectal cancer. CEA levels can be elevated by several sorts of non-cancerous conditions, but note that colon cancer is not a single monoilithic thing - it includes several distinct types and perhaps uknown distinctions. He prefers not to look at CEA at all for people like me, but the other oncologist is pushing for genetic tests, and suggested I do chemo even though it isn't protocol for my stage. I had 11 out of 20 or 21 nodes with cancer. A singular increase in CEA levels is not significant. Unauthorized use of these marks is strictly prohibited. Compared to the median level of 26.8 ng/mL, patients with CEA levels of >69 ng/mL were at a significantly elevated risk for progression. I have really been stressed out over my last CEA level and can't help but think there could be something brewing with the levels going up from after the surgery but I have to try to keep thinking positive thoughts. The CEA test is only one piece of the puzzle. My CEA level on 7/11 was 5.1. National Heart, Lung, and Blood Institute. 11. Other Conditions Can Cause Elevated CA 15-3 Levels. Worried about rising CEA levels. I am guessing you have seen this details (based on your knowledge above), but just a bit of support for you. This must be very scary. Also, anything in the 1.0 - 5.0 is considered "normal".
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